Sequence assembler for amino acid subsequences. Takes a line-separated text file and returns the assembled/merged peptides (using Needleman-Wunsch global alignment) as a text file.
Sequence assembler for amino acid subsequences. Takes a line-separated text file and returns the assembled/merged peptides (using Needleman-Wunsch global alignment) as a text file.
Edit the RunProteinSequenceAssembly.py with your line-separated text file of peptide subsequences and run it.
Contains functions for the “RunProteinSequenceAssembly.py” script.
Validates the algorithm by generating random polypeptides, randomly fragmenting them (in silico fragmentation), and running the assembly on the resulting subsequences. Probably needs more improvement.
Generates a random polypeptide and then fragments in silico at random combinations of sites. Outputs the simulated fragments in a txt file.